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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b944c89c4626011e73b29f55ed8e6b4067db3aa28b35162a87cc55548a35c6' 
  AND token = 'R0qpp10vcYQR5TdMT5n7ZlI0YXPMXGM8ErHz68tK3Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}