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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edd459b1fe5247cafd287b7d01f715de621135e5f2f0a3ea06af0d94b0a8167' 
  AND token = '4VrVVLqBvGls4IaYFFG2Wk+K6Fq8tb3rzOQFdWCiHTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}