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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d3de108588c665aaf8ca05f82a06de2f61357098213300f5ce76e2a35ac737' 
  AND token = '2EeENgFfD4otBSVgVGKjAOy0vu7O6htmlIckRqgU8kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}