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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e227866a402a0eea0bb871e4312c8df7fbb6f860e7e2394b1088cfd65cd5157' 
  AND token = 'Mctz8TXuYA0/1sjwVo12yjLKbJ6OmCo2aCXrU2IQsyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}