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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef4db0a6a6901dbe7f94487a15aba4c9e975d7a41f859a6a241db3f699960d4' 
  AND token = 'XB6VLOd6+qPtyt5gIMAcmC97Rvaip7kw9WrzH6LeQtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}