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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e275ec141700898f68e46fe8fa8f75d0153a549eabe97c9a7eb172f2282d874' 
  AND token = 'ITfAi5wcNUAlN4cu2KhZDjo3JwBZxZQZGGaY/Wicvic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}