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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7204da610cf6fc63cb227f01f261f359c3157a837e2e9f5b7ef541206121f37' 
  AND token = 'Mw9bc4GpVBiDoiOZgDydLEh8QhwetlXHBdcuIkSsFfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}