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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff3a5cece72893a72c5ff9088e5f381a38b1bbaf020bd4aca1ec2063c46b807' 
  AND token = 'T7HV4mM6b5LUZJ97P1Mskq7JtaF2xv2K1BnLqCa0Gs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}