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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd347b2fcfff0fca2ed686287b4579ed3c377befc66234cbd39a77b9d17ad1688' 
  AND token = 'kh9Lqb10zgfdX6TIg0OXVOj0gGdm37Zs/d8/Fn3oGBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}