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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e283d39ff3e499118c68748fd98d951cbba97682cafc3dab56fd81d59e917f0' 
  AND token = '2VbdRu+1ja6dqAc2hEVLFJwZxLgDaoYDPYYVJrIUREg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}