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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1898d9c70d725d334afc18cb38f590939813aea76d7a9cba59cd40116e4a901' 
  AND token = '5XEHCod2AP0KZw1/UfyVUg50Tx6yTzlJHXtoolzK7fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}