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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e3f4d5b4682a658a0bbc62be7799219a986db1c78d7b87906f731d7e43ebcb' 
  AND token = 'l2TIrusXIRaQXo9G0cTiRNQpCxt3CVxwwNXweu9OLL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}