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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72c7dc90e1d73d467433636c2e6b66a4985ef799913927749a021f449a5911c' 
  AND token = 'xdPeJE9hmEDJ/oGxVdMOCUG0xuVu87w+nvxdwK5enQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}