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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b319216b6dc03ac034a7d33c5826d7be0587f36765fe7a68e2220a8f89e806b' 
  AND token = 'EP2q0xawDbWl1jXkOomhUCQAx2vW7+yTG/KB3qtd7tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}