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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b583818ffe22bf1314124a6d717b0bf80818156731ab930f239e3aebffbec37' 
  AND token = 's1tZN5V+pR+i4ItuNcCudn5lM4qn4zpo7CqKMY6TG7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}