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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c7df3c7dc0185ce13af4217d47d7fbe782250d61945c0bb2544a8aaae8c696' 
  AND token = 'd0++42QDpAUyB8oOGF/vqdKptnjR3HHrPIF/HxDr1cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}