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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c836551767ca5f5d758e09caceebbea054fcf4dc2262c1c89fa03a1249f61b01' 
  AND token = 'w3ZS8h+5wkzcZA/l1+TNpRdT6Rkt6ZVEVVeav88+D7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}