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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01847a291d24e4ec8f305c1c2ca62aad884c58cd88a7040ab3c6b85a2e3a7f1b' 
  AND token = 'tOOHDsJjVJfjbp2VH3cekBn8YV0VQ9Xej5tVNPfVI54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}