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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b0e8f286cad127cfd4ec9b6bef96fe854550a7924d8fa76cdb08ca78c1661d' 
  AND token = 'adGfAP9MfmCUIE0z9dWvsd8OJxPM54EQL5ZR0I7vLVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}