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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68ab1b12d8a036e9e438b569b2cd855a5fcfa0463ed76ef0b541c787128621e' 
  AND token = '5+rgUcTr5SNtDSBzx4e5VDxImQlkSDfBH1IggDc+TGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}