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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2265114a1afc6b7d193e61ada841cac18b122461310b27ccbb6274273fb2ce25' 
  AND token = 'K8DRdx8fz+JC9Hfqc68Dok8ZvK72WXwm9xNnHFQkryU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}