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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9dcf48ec8ed540b9c6a447709e8e668299e3c10bf6d43e2eff20f87c41e9993' 
  AND token = '9+CHS+3P4IeWfH2IxZGeMFZGa+hY1iYxxYCnhkbiWe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}