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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d20e995e0d205b30bd2f7384ca4edb1151195c1e5a36f9268fabd1f62caf70' 
  AND token = 'JA4P2a9F7f3xdJmBB6QA2x7FbGzceAnmsi2HDC4dGKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}