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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c696e58f04793c53195e594ed8c268752c72dd45c6c65b3d5861be89cfed8b65' 
  AND token = 'QeON2+qgF376Tgi1E/rgvIl8vd3+5lOa5EMTnfi1w9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}