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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff6d5b60f49b100208c6d054df986db42b3fb9fb3f81d41c261870cb45dcc8b' 
  AND token = 'QFT7po750f7XXhXR5UK/5AlCNXABHT8Te60osoGNtK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}