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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a3da540945fd8de18fdd624261feb25f94291fabf2aed0002e3df07770ec4b' 
  AND token = '0PkU9LF1L57R5jMtoRJWQJKE3BRhvsy+/0Z4mUiSBfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}