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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa39ee9b2fadee88d03d7135d068cc179ce9e028c9248dceda9cd1e1d0a8a6e' 
  AND token = 'NX/i+IzDKUcwjlVynQaLNX/YGoYuFe+e+aqT98hQC4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}