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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647b1225f29782d688e66b594cae269755ca9c989a60f694c960671175de1970' 
  AND token = 'vL3VUGvXaC2NigYmIWp2j7FfjL39sdyE0M1oEoJx540=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}