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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee4e3abea5f53238c6c81cf43c503ad690646ce23a9bfcad7c46d7f287cae2c' 
  AND token = 'f+viphvX43PutSwDGtdSe6D8EDv4zSKPXsqkp3ZV8Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}