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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814c12f1e54aea904f07c40cbd4c1985675265c4b4a325055fa5688fd1a8d1c1' 
  AND token = 'ZfEvxgY17qVomZ0//ZAIh9rLjYxotS4a9ojxnQDrhFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}