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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5cc8043d6475ef0161f7f98b42b83a7173356e1cf4592c204abe6ba34391d7f' 
  AND token = 's6hVJ/jSXJdiZsNDc2l1CQqWrcdMCy4yjWiMtB+HT5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}