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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc739fc07bad1171858949fc8f4e05df8edbeaa93d90a5a4e49a545858e6e215' 
  AND token = 'wFqWBTgOljQpQZr4TrvcfsOTxdojvKh2S65o1FoOWKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}