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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e448267b8d4f605c8a8d94725a11c4c9d32e2c693cfb2f2a9463045c89b1a6e' 
  AND token = 'PoJv8bFMk6ep9mfEPYWuZg7tYZsAtdZZ5/E5L43a4mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}