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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad654716a9edd43418ad8f14d6fbb8f1e5330971ee573cd3e219e03930cb154' 
  AND token = 'EI9kbINSKlBnyNbzclvhLxi/9AypBR9+nS3XzlByc7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}