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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cddd19d2b1b857e7946d5eebbde83c7bc930083fd34dd5c912c6e9ad709f956' 
  AND token = 'Z0eJ4aSpSuT4b20+HFLBymq4mRsgVQYAoy7z+ortO0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}