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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '607c07c21198c0f51d3a0d09e9a3a46eb3a396761b718f362c8c214b1bfa4e62' 
  AND token = 'ZVRw+fO0vorjIh1t2cb/Uh0cFVEljgOk8u6MunXlvjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}