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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6a178e8caca07cba9025f5408ad4122997a4b19932507055454b159b4fa206' 
  AND token = '7s4V9p3B7eowpjVz4wI9XMOEr2Uf0mKRNydEuCdUx6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}