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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ff79c45873830a69eb09f99e3c107746d7b000f26cb6d277b4ba69c968d1a3' 
  AND token = '74SGQ2LFWCS5KOEyo8coyYljaQQlNmKHlJO1AKQQhlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}