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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849c73d918bb6d46ea171c219014ca07f62ea81f7a99f17118b89b64ae0df071' 
  AND token = 'o0w9Yp8DSqJ5gPHYGqmrer+Q4WifzSuruoU6yLg7CUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}