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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35dce96c9c4e87c69ce07007aca89878674a1be2b6cb275a0eb529e60e565139' 
  AND token = 'ePmJu3p2rWWZUdZn4nvfdx11nX17/ZvqxLFE2qp+PnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}