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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc22366c38c116a804a43526ce25008c39bbbd7016ef73dc76cc4c1d10cea30' 
  AND token = 'XwmlNzlhBJCFOyJoeaRTNd0+vFYX64yIb+2DUKbp8So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}