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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5afd7edfec665cef244d15131ae6a8bab674fcd6b0050d2e037699f2e1580aca' 
  AND token = '5IJMmyBZ2eDtubWafgDPhfoMg6VvJy7v43Arrfmy0yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}