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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e4824c43290b7b88d85555ccb97d1b07626024f5f8e831d5eefa7f4b467209' 
  AND token = 'B15mqmf+ixrA/rnWGb4b4W9Y9XJsJhOLY9acAqkkPnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}