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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8accbef495e83f8134453c317e3e9fb7345edd46b567108396b5b5d6fc04a5bb' 
  AND token = 'U8H1spIvmIaERVStthk++FCweBuqB6U/r3F0mF310Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}