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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed04537e74d0b666bdc27a5f8521d0b21464760cf27c1e9b1113d10484c73b58' 
  AND token = 'msNRci6mQd9i1RiRvEGm6PNfgRsH3d5u+C26mdTRH0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}