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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '569fa096cb56e9977d7f33a9f88a1d129eb6b914ae9378228f9f0e67d18a7654' 
  AND token = 'tZ3+7EYZHPKld4ACI/1cvbkWc1wJ0u8ZGj7QinZGbNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}