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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a40af99a80fe98f48ee4bb988610d2faea3c4216c64a8660ca18df8d3340f92' 
  AND token = 'Qsg0eQ/LnQqIjsyJbxSmnXfXmrX1qHXUK0tHOBNbPCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}