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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215f5221821cba9d4d620758b64ad2809a9fc4ba0080b3a5b7230ccdbda8e8d9' 
  AND token = 'fwVi6t1sVRRwoMmeE4Zo4BCgTHSzWDH3R/LPB+XSkX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}