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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3553982e8e534914ee39fb4e0d0b03f14cb48ac78708a0712ca20e3f0905be4d' 
  AND token = '+X+lSB36oKh4cQyAYrH4w0dvVbaeL7FlStGMfgj7c3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}