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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4a18fe2fd1df90ab341cf70611cc7dc468f371e83fe54ee4bef54365e81bbe' 
  AND token = 'Tcwymc9yHtdd90F4TyYFIO4pO48RMkjciOQw8Tmz6C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}